How many times OPV should be given?
OPV is the WHO-recommended vaccine for the global eradication of polio. Each child requires just two drops per dose to be immunized against polio. Usually administered four times if the EPI schedule is followed, OPV is safe and effective in providing protection against the paralyzing poliovirus.
Why OPV is given orally?
The action of oral polio vaccine (OPV) is two-pronged. OPV produces antibodies in the blood (‘humoral’ or serum immunity) to all three types of poliovirus, and in the event of infection, this protects the individual against polio paralysis by preventing the spread of poliovirus to the nervous system.
Why is IPV better than OPV?
IPV is also more expensive and more difficult to administer than OPV. OPV, on the other hand, provides better mucosal immunity than IPV, but because it’s a live virus, it can replicate and revert to a neurovirulent form that endangers its host and could fuel outbreaks.
What are the side effects of OPV vaccine?
Common side effects of Orimune include fever, pinkeye (conjunctivitis), severe fatigue, injection site reactions (hives, itching, and skin redness), irritability, and loss of appetite. The adult dose of Orimune is 0.5 mL taken orally initially, then repeated 8 weeks later.
Is OPV required after IPV?
IPV is recommended in addition to OPV and does not replace OPV. IPV is a very safe vaccine in humans, whether used alone or in combination vaccines. No serious adverse events have been reported, only minor side effects.
Why is OPV no longer used?
According to the World Health Organization, routine immunization with OPV must cease after the eradication of poliovirus because of the danger of outbreaks of circulating vaccine-derived poliovirus and the risk of VAPP.
Who invented OPV?
At what age polio occurs?
Key facts. Polio (poliomyelitis) mainly affects children under 5 years of age. 1 in 200 infections leads to irreversible paralysis. Among those paralysed, 5% to 10% die when their breathing muscles become immobilized.
Does polio mutate?
As a result of such circulating vaccine-derived poliovirus (cVDPV) strains, polio outbreaks have periodically recurred in regions that have long been free of the wild virus, but where vaccination rates have fallen.
Can you be born with polio?
Can post polio syndrome be inherited? No. Post polio syndrome is not inherited . Post polio syndrome only affects people who have had polio.